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06.01.2014   

             Research communications                 

Animal Centre.

In 2013

1. A PRELIMINARY  STUDY  OF  THE  SEROPREVALENCE  OF LEPTOSPIROSIS  IN  DOMESTIC DOGS IN SUBURBS  OF COLOMBO, SRI LANKA.

M.G.Thammitiyagodage(1), P. Somaratne(1), K.C.R  Perera(1) and M. A. Roshan Priyantha(2), 

1. Medical Research Institute, No 527, Dr. Danister de Silva Mawatha, Colombo 8,  Sri Lanka.

2. Veterinary Research Institute, P.O. Box 28, Gannoruwa,  Peradeniya.

                                    Click here for Abstract

 

Upto 2012

Dr. Sharmini Jayasekera, veterinary surgeon who was trained under JICA cooperation

initiated the work in collaboration with Japanese team to establish the animal centre. She

worked as the Head of the Section since 1989 to 2010 and she pioneered the research

activities in the animal centre, MRI.

 

(01)Thabrew MI, Samarawickrema N, Chandrasena LG, Jayasekera S.

Effect of oral supplementation with vitamin E on the oxido-reductive status of red

blood cells in normal mice and mice subject to oxidative stress by chronic

administration of Adriamycin. Annals of Clinical Biochemistry 1999, 36:216-220

Received presidential awards  1999

 

(02)Thammitiyagodage MG, Munasinghe TMJ, Peiris H.

Making Wistar rat’s hypercholesterolaemic by feeding a diet containing 0.25%

cholesterol and 5% butter fat.

Sri Lanka Veterinary Journal (46) (1999). (1); 13-14.

 

(03)Thabrew MI, Samarawickrema N, Chandrasena LG, Jayasekera S.

Protection by garlic against Adriamycin induced alteration in the oxido-reductive

status of mouse red blood cells. Phototherapy Research 14, 215-217(2000)

 

(04)Samaranayake MDP, Wickramasighe SMDN, Angunawela P,

Jayasekera S, Seneviratne AGDH, Iwai S, Fukushima S.

Inhibition of chemically induced liver carcinogenesis in Wistar rats by garlic

(Allium sativum). Phytotherapy Research14, 561-567 (2000)

Received presidential awards 2000

 

(05)Jayasekera S, Arseculeratne SN, Atapattu DN, Kumarasiri R,

Tilakaratne WM.

Cell-mediated immune responses (CMIR) to Rhinosporidium seeberi in mice.

Mycopathologia152; 69-79 (2000)

 

(06)Ariyasena DD, Janz ER, Jayasekera S, Abeysekera AM.

Inhibitory effect of bitter principle of Palmyra (Borassus flabellifer L) fruit pulp

on the growth of mice: evidence using bitter and non bitter fruit pulp.

Journal of the Science of Food and Agriculture 80:1763-1766 (2000)

 

(07)Ekanayake S, Janz ER, Abeysekera AM, Jayasekera S.

Effect of Canavalia gladiata seed meal on impregnated mice

Journal of Science, Eastern University of Sri Lanka (2001) Vol.2No.1, p1-8

Received presidential awards 2001

 

(08)Iddamaldeniya SS, Wickramasinghe SMD, Thabrew MI, Rathnatunga

N, Thammitiyagodage MG.

Protection Against Di- Ethyl Nitrosamine Induced Hepatocarcinogenesis by

Indigenous remedies.

Journal of Carcinogensis 2003: 2: 6: 9 (18 the Oct 2003)

 

(09)Vindica Sumudini KA, Janz ER, Jayasekera S, Wickramasighe

SMDN. The Neurotoxic effect of (Borassus Flabellifer) flour re-visited

Nutritional Journal of Food and Nutrition volume 55, number 8 (December 2004)

607-614

(10)Rajapakshe RPAS, Perera WSR, Ihalamulla RL, Weerasena KH, Jayasinghe

S, Sajeewani HBR, Thammitiyagodage MG and Karunaweera ND.

Study of dirofilariasis in selected areas in the western province.

Ceylon Medical Journal Vol. 50 No 2 June 2005.

 

(11)Iddamaldeniya SS, Wickramasinghe SMD, Thabrew MI, Rathnatunga

N, Thammitiyagodage MG.

Toxicity study of a decoction comprised of Nigella sativa, Hemidesmas indicus

and Smilax glabra.  Ceylon Medical Journal Vol. 50 No 2 June 2005.

 

(12)Iddamaldeniya SS, Thabrew MI,  Wickramasinghe SMD, Rathnatunga

N.Thammitiyagodage MG.

A long – term investigation of the anti hepatocarcinogenic potential of an

indigenous medicine comprised of Nigella sativa, Hemidesmus indicus, and

Smilax glabra Journal of Carcinogenesis 2006,5:11(9th May 2006)

 

(13)AthiththanLV , JayaratneSD,  Peiris H, and  Jayasekera S.

The effect of milk protein and curd on serum Angiotensin Converting Enzyme

activity and lipid profile.

Journal of National Science Foundation Sri Lanka 2009 37 (3) 203

 

(14)Thammitiyagodage MG, Chandrasiri P, Kumari Dissanayake HMR

Puvandiran S and Jayathunga S.

Identification of Serovas of Leptospira among Buffaloes and Buffaloe Farmers

In Homagama Veterinary Division in Sri Lanka.  Sri Lanka Veterinary journal (SLVJ) 2007- 54-55 (A) pp7-10.

 

Communications (Oral presentations)

 

(01)Samaranayake MDP, Wickramasighe SMDN, Jayasekera S.

Effect of garlic on diet induced hypercholesterolemia in Wistar rats.

Annual Academic sessions 1998, University of Sri Jayewardenepura.

 

(02)Samaranayake MDP, Wickramasighe SMDN, Jayasekera S.

Effect of cholesterol-enriched diets on blood cholesterol levels in Wistar rats, 54th

Annual session Sri Lanka Association for the Advancement of science. (1998)

 

(03)Samaranayake MDP, Wickramasighe SMDN, Angunawela P, Jayasekera

S, Seneviratne AGDH, Iwai S, Fukushima S.

Inhibition of hepato-carcinogenisis in Wistar rats by garlic (Allium sativum),

112Th Anniversary Academic Sessions, Sri Lanka Medical Association (1999)

 

(04)Samaranayake MDP, Wickramasighe SMDN, Jayasekera S.

Reduction of risk of liver cancer by garlic (Allium sativum) in

hypercholesterolaemic Wistar rats. Chemistry in Sri Lanka (1999)

 

 

 

(05)Goonaratne PS, Janz ER, Illeperuma N, Jayasekera S.

Determination of L-Dopa In Mucuna utilis and feeding trials in ICR mice.

Chemistry in Sri Lanka (1999)

 

(06)Ekanayake S, Janz ER, Abeysekera AM, Jayasekera S.

Some anti nutritional factors of Canavalia gladiata. Chemistry in Sri Lanka

(1999)

 

(07)Ariyasena DD, Janz ER, Jayasekera S, Abeysekera AM.

Evidence to link the bitter principle of Palmyra (s) fruit

pulp with the inhibition of weight gain in ICR mice. Chemistry in Sri Lanka

(2000)

 

(08)Thammitiyagodage MG, Colambage G, Weerasinghe IS, Jayasekera

S, Junaid M. (2000).

An investigation of Trypanasomiasis in the animal

population of Chena -Kudiruppu area in Kalmunai and possibility of zoonotic transmission.

52 nd Annual Convention of Sri Lanka Veterinary Association and Asian

Regional Meeting of the Commonwealth Veterinary Association.

 

(09)Thammitiyagodage MG, Thabrew MI, Munasinghe

TMJ, Kumara WGSS (2001).

An investigation of possible lipid lowering properties of Alliums Porum (Leek) in

Wister rats.

53 rd annual convention and scientific session of Sri Lanka Veterinary

Association

 

(10) Iddamaldeniya SS, Wickremesinghe SMDN, Thabrew I, Ratnatunga

N,Thammitiyagodage MG, Jayathilake N, Ramadasa SS. (2002).

Inhibition of chemically inducible Glutathione. S Transferase placental form

(GST- P) By Plant extracts.

Annual Academic Sessions. The collage of Pathologist of Sri Lanka.

 

(11)Iddamaldeniya SS, Wickremesinghe SMDN, Thabrew I, Ratnatunga

N, Thammitiyagodage MG and Jayathilake N.

Protection against diethylnitrosoamine (DEN) induced hepatocarcinogenisis by an

Indigenous medicine comprised of Nigella sataiva, Smilax glabra and

Hemidesmus Indicus. World Ayurveda Congress 2002

 

(12)Subashini RM, Thammitiyagodage MG, Jayasekera S. and

 Kumara WGGS (2002).

Detection of possible hypoglycaemic activity and toxic effect of `Cogent db ‘

on normoglycaemic Wistar rats. Sri Lanka Association for the Advancement of

Science (SLAAS).Proceedings of the 58 th annual Session, part 1 –

Abstract of Presentations.

 

(13)Iddamaldeniya SS, Wickramasinghe SMDN, Thabrew MI, Ratnatunge

Thammitiyagodage MG. and Jayathilake N.

Protection against diethylnitrosamine (DEN) induced hepatocarcinogenesis in rats

by an indigenous herbal remedy.

Sri Lanka Association for the Advancement of Science (SLAAS).

Proceedings of the 58 th annual Session, part 1 –Abstract of Presentations.

 

(14)Thammitiyagodage MG, Jayasekera S, Galagoda GCS, Rashid

L,Ekanayake N, Bandumala KAP.

Investigation of sudden deaths among crows (Corvus splendens) in Colombo

municipality area.

55th Annual Convention and Scientific Sessions of Sri Lanka Veterinary

Association 2003.

 

(15) Iddamaldeniya SS, Thabrew MI, Wickramasinghe SMDN, Rathnatunga

N, Thammitiyagodage MG.

Traditional remedy comprised of Nigella sativa seeds, Hemidesmes indicus root

And Smilax glabra rhizomes with possible anti hepatocarsinogenic potential.

56thAnnual Convention of the Sri Lanka Veterinary Association 2004.

 

(16)Thammitiyagodage MG, Chandrasiri P, Dissanayake HMRK,

Puwanendran S. and Jayathunge S.

An investigation of the relationship between Leptospirosis in humans and in

buffalo of Homagama veterinary division.

56thAnnual Convention of the Sri Lanka Veterinary Association 2004.

 

(17) Rajapakshe RPAS, Perera WSR, Ihalamulla RL, Weerasena KH,

Jayasinghe S, Sajeewani HBR,Thammitiyagodage MG &KarunaweeraND.

Study of human and canine dirofilariasis in a selected area in the western

province.

The Annual Academic Sessions Sri Lanka College of microbiologists 2004

 

(18) LankanandaBD, ThammitiyagodageMG, KumaraWGSS, Weerasinghe GAK.

Effect of aqueous and methanolic bark extract of Canarium zelanicum (family: Burseracae) in Plasmodium yoelii murine malarial model.

 

(19) Galhena BP, ThabrewMI, Thammitiyagodage MG.

Investigation of the antioxidant activity of a herbal decoction with anti-

Carcinogenic properties.

Sri Lanka Association for Advancement of Science

Proceedings of the 63rd annual Sessions-2007.Part 1-Abstracts

 

(20) Athiththan LV, Peiris H,  Jayasekera S and  Jayaratne SD.

Effect of whey protein on angiotensin converting enzyme activity and lipid

profile of wistar rats

Proceedings of the 63rd annual Sessions-2007.Part 1-Abstracts p10

Sri Lanka Association for Advancement of Science

Awarded the 1st prize for best oral communication

 

(21) Athiththan, LV, Peirs, H, Jayasekera, S and Jayaratne SD. A study on the

effect of curd and casein on serum angiotensin converting enzyme activity and

lipid profile in male Wistar rats. 59th Annual Convention and Scientific Sessions

of the Sri Lanka Veterinary Association. 2007 (17).

 

(22) Thammitiyagoda MG,Gunatilake  MM, Jayasekera S, Gunaratne UKSC, Kumara WGSS.

and Abeynayake . Effect of bore well water obtained from villages in the(NCP) with high

prevalance of chronic kidney disease (CKD) in rats. Sri Lanka Association for Advancement of Science

Proceedings of the 65th annual Sessions-2009. Part 1-Abstracts

 

(23) Thammitiyagodage MG, Gunatillaka MM, Jayasekera S , Jayathissa R,

GunarathneUKSC, Jayamanna S, Kumara WGSS and AnenayakeP.

Quetionnaire Based Study to Develop a Laboratory Animal Model to Identify

The Etiology of Chronic Kidney Disease of Unknown Etiology (CKDu) in North

Central Province of Sri Lanka.

61st Annual Convension of the Sri Lanka Veterinary Association.27th March

2009.

 

(24) Thammitiyagodage MG, Gunathilaka MM, Jayasekera S,

Udayangani DIE,  Gunarathne UKSC, AbenayakeP.

Is there a relationship between diminished GFR, elevated liver enzymes levels &

Chronic Kidney Disease in North Central Province of Sri lanka.

3rd Svastha International Ayurveda Conference 2nd to 3rd January 2010.

 

(25) Thammitiyagodage MG, Gunatilake MM, Jayasekera S, Horadagoda N,

JayathilakeMMU, GunarathneUKSC, Ekanayake N, Abenayake P.

Periglomerular and Peritubular Non Suppurative Interstitial Nephritis In Wistar

Rats Given Bore Well Water From North central Province (NCP) of Sri Lanka.

10th South East ASIA Regional Scientific Meeting of The International

Epidemiological Association 23rd-26th May 2010.

 

(26) Thammityagodage MG.

Social Approach to Bioethics in Animal Experiment in Sri Lanka, Social

Scientific Approach to Bio Ethics Conference,London,5th to 7th January 2011.

 

(27) Thammitiyagodage MG, Rathnayake C, Gunatillaka MM, Ekanayaka N, JayatissaR, GunarathneUKSC ,  Jayathilake WMMU.

Histopathological changes in liver and renal tissues in Wistar rats given bore well water from CKDu endemic areas in North Central Province

125th Anniversary International Medical Congress of Sri Lanka Medical Association(2012).

S.Ramachandran award for best communication in nephrology

 

(28) Tharaka Prasad, Thammitiyagodage MG, Karunakaran R, Kothalawala H, Lilani Karunanayake and Deepal Gajadeera.

Isolation of Newcastle disease virus in the pelagic bird, Sooty Tern (Onychoprion fuscatus) in Sri Lanka.

Abstract of 64th Annual convention of the Sri Lanka Veterinary Association (2012)

 

(29) Rodrigo WWP, Thammitiyagodage MG, Dasanayake RS, Weerasena OVDSJ and Karunanayake EH.

Production of polyclonal antibodies against recombinant uncharacterized protein of Setaria digitata using New Zealand White rabbits. Proceedings of the 6th biennial scientific sessions of Allegy and Immunology Society of Sri Lanka 2012.

 

(30) Rodrigo WWP, Dasanayake RS, Karunanayake EH, Weerasena OVDSJ and Thammitiyagodage MG.

Production of antiserum for uncharacterized protein of Setaria digitata using New Zealand White rabbits.

Proceedings of 5th Annual Scientific sessions of Institute of Bio chemistry, Molecular Biology, and Biotechnolgy (IBMBB) 2012.

 

(31) Thammitiyagodage MG, Karunakaran R, Pimburage RMS, Jayasinghe DN. Prolonged Swine anaesthesia without gaseous maintenance . Proceedings of 68th Annual scientific sessions Sri Lanka Association for Advancement of Science 2012.

 

(32) Thammitiyagodage MG, Gunatillaka MM, Ekanayaka N ,  Rathnayake C, Horadagoda NU, Jayatissa R, Kumara WGSS, Gunaratne UKSC.

Impact of the composition of  selected dug well water from North Central Province (NCP) in the development of interstitial nephritis, hepatocellular carcinoma  and hepatitis in Wistar rats.

Scientific sessions MRI Research day 2012.

Awarded 2nd prize for oral communication

 

(33)  Thammitiyagodage MG, Somaratne P, Perera KCR, Roshan Priyantha MA.

A preliminary study of the seroprevalence of Leptospirosis in domestic dogs in suburbs of Colombo Sri Abstracts of  65th Annual Convention of Sri Lanka Veterinary association,2013

 

Poster Presentations

 

(01)Obeysekera N, Thammitiyagodage MG.

Sublingual Edema of a Dog

53thAnnual Convention of the Sri Lanka Veterinary Association 2001.

 

(02)Ekanayake S, Jayasekera S, Thammitiyagodage MG. and Kumara WGSS.

A study of the estrus cycle and pregnancy of ICR mice bred and maintained at

the MRI.

Abstract of Papers 4th Research Session, Faculty of Graduate Studies, University

of Sri Jayawardenepura.

 

(3) Iddamaldeniya SS, Thabrew MI, Wickramasinghe SMDN, Rathnatunga

N, Thammitiyagodage MG.

Traditional remedy with possible antihepatocarcinogenic potential.

117th Annual Academic Sessions Sri Lanka Medical Association 2004

 

(4) Thammitiyagodage MG,  Jayasekera S,  Obayasekera N.

Ethical and legal aspects of animal experiments in Sri Lanka.

13th congress on Alternatives to Animal Testing- University of Linz, Austria.

2006

 

(5) Thammitiyagodage MG, Somaratne P, Perera KCR, Karunakaran R.

Domestic canine vaccination patterns and methods of rearing them in suburban settings in Colombo, Sri Lanka.

Abstract of 3rd Rabies in Asia Conference (RIACON) 2011

 

(6) Karunakaran R, Thammitiyagpdage MG, Seneviratna RDeS,  KumaraWGSS,  LiyanageTK and Lilani Karunanayake.

 Occurrence of Clostridium sordellii in sheep  at MRI.

Abstracts of 64th Annual convention of the Sri Lanka Veterinary Association(2012).